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Update on the Mechanisms of Antibiotic Resistance and the Mobile Resistome in the Emerging Zoonotic Pathogen Streptococcus suis
- Source :
- Microorganisms, Microorganisms, MDPI, 2021, 9 (8), pp.1765. ⟨10.3390/microorganisms9081765⟩, Microorganisms, Vol 9, Iss 1765, p 1765 (2021)
- Publication Year :
- 2021
- Publisher :
- HAL CCSD, 2021.
-
Abstract
- International audience; Streptococcus suis is a zoonotic pathogen causing important economic losses in swine production. The most commonly used antibiotics in swine industry are tetracyclines, beta-lactams, and macrolides. Resistance to these antibiotics has already been observed worldwide (reaching high rates for macrolides and tetracyclines) as well as resistance to aminoglycosides, fluoroquinolones, amphenicols, and glycopeptides. Most of the resistance mechanisms are encoded by antibiotic resistance genes, and a large part are carried by mobile genetic elements (MGEs) that can be transferred through horizontal gene transfer. This review provides an update of the resistance genes, their combination in multidrug isolates, and their localization on MGEs in S. suis. It also includes an overview of the contribution of biofilm to antimicrobial resistance in this bacterial species. The identification of resistance genes and study of their localization in S. suis as well as the environmental factors that can modulate their dissemination appear essential in order to decipher the role of this bacterium as a reservoir of antibiotic genes for other species.
- Subjects :
- Microbiology (medical)
plasmids
antibiotic resistance
Streptococcus suis
medicine.drug_class
QH301-705.5
ICEs
[SDV]Life Sciences [q-bio]
Antibiotics
competence
Review
Biology
GIs
Microbiology
biofilm
IMEs
03 medical and health sciences
Antibiotic resistance
Plasmid
prophages
Virology
medicine
Biology (General)
Prophage
030304 developmental biology
0303 health sciences
mechanisms
030306 microbiology
resistance genes
mobile genetic elements
biology.organism_classification
UCSs
Resistome
Horizontal gene transfer
horizontal gene transfer
Mobile genetic elements
conjugation
Subjects
Details
- Language :
- English
- ISSN :
- 20762607
- Database :
- OpenAIRE
- Journal :
- Microorganisms, Microorganisms, MDPI, 2021, 9 (8), pp.1765. ⟨10.3390/microorganisms9081765⟩, Microorganisms, Vol 9, Iss 1765, p 1765 (2021)
- Accession number :
- edsair.doi.dedup.....3112978983d23d91f6528fd446617b27