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Curcumin potentiates laryngeal squamous carcinoma radiosensitivity via NF-ΚB inhibition by suppressing IKKγ expression
- Source :
- Journal of Receptors and Signal Transduction. 40:541-549
- Publication Year :
- 2020
- Publisher :
- Informa UK Limited, 2020.
-
Abstract
- Context: Curcumin has shown efficacy in promoting radiosensitivity combined with radiotherapy. However, the role and mechanism of curcumin on radiosensitivity in laryngeal squamous cell cancer (LSC...
- Subjects :
- 0301 basic medicine
Radiation-Sensitizing Agents
Curcumin
medicine.medical_treatment
Antineoplastic Agents
Apoptosis
Context (language use)
Radiation Tolerance
Biochemistry
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Biomarkers, Tumor
Tumor Cells, Cultured
Humans
Medicine
Radiosensitivity
Phosphorylation
Laryngeal Neoplasms
Molecular Biology
Cell Proliferation
Squamous cell cancer
business.industry
NF-kappa B
Nf κb inhibition
NF-κB
Cell Biology
I-kappa B Kinase
Squamous carcinoma
Gene Expression Regulation, Neoplastic
Radiation therapy
030104 developmental biology
chemistry
030220 oncology & carcinogenesis
Carcinoma, Squamous Cell
Cancer research
sense organs
business
Signal Transduction
Subjects
Details
- ISSN :
- 15324281 and 10799893
- Volume :
- 40
- Database :
- OpenAIRE
- Journal :
- Journal of Receptors and Signal Transduction
- Accession number :
- edsair.doi.dedup.....30d612987dad7ad227eb924de2eb78f7