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Nonlinear effects of respiration on the crosstalk between cardiovascular and cerebrovascular control systems
- Source :
- Philosophical transactions. Series A, Mathematical, physical, and engineering sciences. 374(2067)
- Publication Year :
- 2016
-
Abstract
- Cardiovascular and cerebrovascular regulatory systems are vital control mechanisms responsible for guaranteeing homeostasis and are affected by respiration. This work proposes the investigation of cardiovascular and cerebrovascular control systems and the nonlinear influences of respiration on both regulations through joint symbolic analysis (JSA), conditioned or unconditioned on respiration. Interactions between cardiovascular and cerebrovascular regulatory systems were evaluated as well by performing correlation analysis between JSA indexes describing the two control systems. Heart period, systolic and mean arterial pressure, mean cerebral blood flow velocity and respiration were acquired on a beat-to-beat basis in 13 subjects experiencing recurrent syncope episodes (SYNC) and 13 healthy individuals (non-SYNC) in supine resting condition and during head-up tilt test at 60° (TILT). Results showed that JSA distinguished conditions and groups, whereas time domain parameters detected only the effect of TILT. Respiration affected cardiovascular and cerebrovascular regulatory systems in a nonlinear way and was able to modulate the interactions between the two control systems with different outcome in non-SYNC and SYNC groups, thus suggesting that the analysis of the impact of respiration on cardiovascular and cerebrovascular regulatory systems might improve our understanding of the mechanisms underpinning the development of postural-related syncope.
- Subjects :
- Mean arterial pressure
medicine.medical_specialty
Supine position
General Mathematics
0206 medical engineering
General Physics and Astronomy
02 engineering and technology
030204 cardiovascular system & hematology
Baroreflex
Cerebral autoregulation
Cardiovascular System
03 medical and health sciences
Physics and Astronomy (all)
0302 clinical medicine
Engineering (all)
Conditional joint symbolic analysi
Internal medicine
Respiration
medicine
Heart rate variability
Autonomic nervous system
Conditional joint symbolic analysis
Head-up tilt
Mathematics (all)
business.industry
General Engineering
020601 biomedical engineering
Cerebral blood flow
Settore ING-INF/06 - Bioingegneria Elettronica E Informatica
Cardiology
business
Subjects
Details
- ISSN :
- 1364503X
- Volume :
- 374
- Issue :
- 2067
- Database :
- OpenAIRE
- Journal :
- Philosophical transactions. Series A, Mathematical, physical, and engineering sciences
- Accession number :
- edsair.doi.dedup.....30c1d291279b10fc62959744ea977768