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Supplementary Figure 2 from Human Regulatory T Cells Do Not Suppress the Antitumor Immunity in the Bone Marrow: A Role for Bone Marrow Stromal Cells in Neutralizing Regulatory T Cells

Authors :
Tuna Mutis
Anton C. Martens
Henk M. Lokhorst
Gert Storm
Richard W.J. Groen
Bianka Martini
Henk Rozemuller
Maarten E. Emmelot
Teun Guichelaar
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

PDF file - 54K, Human Tregs allow GvT against murine lymphoma tumors. Human PBMC were infused alone or together with expanded human Tregs to treat immune deficient mice carrying murine Luciferase+ A20 lymphoma cells in the bone marrow. PBMC (n=10), PBMC + Treg (n=9), untreated control group (n=10) (A) Kaplan Meier survival curves of mice, which all were sacrificed due to paralysis ***, p

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....30b9aff7e08e41da3d7ae0725e0da910