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BYKdb: the Bacterial protein tYrosine Kinase database
- Source :
- Nucleic Acids Research, Nucleic Acids Research, Oxford University Press, 2012, 40 (Database issue), pp.D321-4. ⟨10.1093/nar/gkr915⟩, Nucleic Acids Research D1 (40), D321-D324. (2012), Nucleic Acids Research, Oxford University Press, 2012, 40, Nucleic Acids Research, 2012, 40 (Database issue), pp.D321-4. ⟨10.1093/nar/gkr915⟩
- Publication Year :
- 2012
- Publisher :
- HAL CCSD, 2012.
-
Abstract
- International audience; Bacterial tyrosine-kinases share no resemblance with their eukaryotic counterparts and they have been unified in a new protein family named BY-kinases. These enzymes have been shown to control several biological functions in the bacterial cells. In recent years biochemical studies, sequence analyses and structure resolutions allowed the deciphering of a common signature. However, BY-kinase sequence annotations in primary databases remain incomplete. This prompted us to develop a specialized database of computer-annotated BY-kinase sequences: the Bacterial protein tyrosine-kinase database (BYKdb). BY-kinase sequences are first identified, thanks to a workflow developed in a previous work. A second workflow annotates the UniProtKB entries in order to provide the BYKdb entries. The database can be accessed through a web interface that allows static and dynamic queries and offers integrated sequence analysis tools. BYKdb can be found at http://bykdb.ibcp.fr.
- Subjects :
- MESH: Databases, Protein
Protein family
Sequence analysis
MESH: Sequence Analysis, Protein
[SDV]Life Sciences [q-bio]
MESH: Molecular Sequence Annotation
Biology
computer.software_genre
MESH: Protein-Tyrosine Kinases
User-Computer Interface
03 medical and health sciences
Bacterial Proteins
Sequence Analysis, Protein
Genetics
Databases, Protein
PHOSPHORYLATION
MESH: Bacterial Proteins
ComputingMilieux_MISCELLANEOUS
030304 developmental biology
Sequence (medicine)
MESH: User-Computer Interface
Structure (mathematical logic)
0303 health sciences
Bacteria
Database
030302 biochemistry & molecular biology
Molecular Sequence Annotation
Articles
Protein-Tyrosine Kinases
MESH: Bacteria
Workflow
UniProt
User interface
computer
Subjects
Details
- Language :
- English
- ISSN :
- 03051048 and 13624962
- Database :
- OpenAIRE
- Journal :
- Nucleic Acids Research, Nucleic Acids Research, Oxford University Press, 2012, 40 (Database issue), pp.D321-4. ⟨10.1093/nar/gkr915⟩, Nucleic Acids Research D1 (40), D321-D324. (2012), Nucleic Acids Research, Oxford University Press, 2012, 40, Nucleic Acids Research, 2012, 40 (Database issue), pp.D321-4. ⟨10.1093/nar/gkr915⟩
- Accession number :
- edsair.doi.dedup.....30a8c2332ae3b259383eaefc1ba62ab2