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A rapid real-time quantification in hybrid paper-polymer centrifugal optical devices
- Source :
- Biosensorsbioelectronics. 126
- Publication Year :
- 2018
-
Abstract
- The research progress in the centrifugal microfluidic platform provides great opportunities for simple and effective analytical measurements in a variety of areas including biomedical engineering. In this study, we propose an optical reader that can measure the transmittance in a very sensitive and rapid manner on a hybrid paper-polymer centrifugal disc platform. This device enables real-time monitoring of multiple samples by measuring the absorbance of the light transmitted through the paper integrated on the disc between the light emitting diode (LED) and the photodiode (PD) regardless of the ambient light condition. To confirm its efficiency, we analyzed one of the blood's important indicators, glucose in a successful manner within 10 s without any additional complex image analysis. In addition, we discussed the results by comparing with the reflectance-based methods and with those of the previously reported studies by introducing a figure of merit to evaluate the performance of the assay.
- Subjects :
- Paper
Materials science
Light
Polymers
Microfluidics
Biomedical Engineering
Biophysics
Measure (physics)
Centrifugation
02 engineering and technology
Biosensing Techniques
01 natural sciences
law.invention
Absorbance
Optical reader
law
Electrochemistry
Transmittance
Figure of merit
Humans
business.industry
010401 analytical chemistry
General Medicine
021001 nanoscience & nanotechnology
0104 chemical sciences
Photodiode
Glucose
Optoelectronics
Colorimetry
0210 nano-technology
business
Biotechnology
Light-emitting diode
Subjects
Details
- ISSN :
- 18734235
- Volume :
- 126
- Database :
- OpenAIRE
- Journal :
- Biosensorsbioelectronics
- Accession number :
- edsair.doi.dedup.....30a5181db3cd487dadc15baacaec629d