Additional file 1 of Genetic architecture of cardiometabolic risks in people living with HIV

Additional file 1: Table S1. A summary of genotyping and imputation platforms utilized to generate the final study data set. Table S2. Description of previously published genome-wide association studies (GWAS) in European populations that were used in polygenic risk score analyses. Table S3. Number of variants used to derive various polygenic risk scores for different traits and diseases. Table S9. Number of expression quantitative trait loci controlled by HIV-specific loci in CD14+ monocytes from Fairfax et al. [51]. Fig. S1. Fraction of expression quantitative trait loci among the HIV-specific loci (see the Methods section for details) compared to all other loci. HDL, high-density lipoprotein; LDL, low-density lipoprotein; TG, triglycerides; SNP, single nucleotide polymorphism. CD14, CD14+ monocytes at baseline; INF, activated CD14+ monocytes following induction with interferon-γ; LPS2, activated CD14+ monocytes following a 2-h induction with lipopolysaccharide; LPS24, activated CD14+ monocytes following a 24-h induction with lipopolysaccharide. SNP, single nucleotide polymorphism.