Acronyols A and B, new anti-inflammatory prenylated phloroglucinols from the fruits of Acronychia crassipetala

Authors :: Paul Reddell
Shintu Mathew
Ahilya Singh
Ritesh Raju
Gerald Münch
Publication Year :: 2021
Publisher :: Taylor & Francis, 2021.
Abstract: Two new phloroglucinols, acronyols A (1) and B (2) along with the four known (3–6) pholoroglucinols were identified following anti-inflammatory activity guided fractionation from the fruits of Acronychia crassipetala (family Rutaceae). The pholoroglucinols (1–6) were evaluated for their inhibitory effects on NO production and downregulation of TNF-α in RAW 264.7 macrophage cell lines.

Subjects :: Family rutaceae
Traditional medicine
biology
Chemistry
medicine.drug_class
Organic Chemistry
Plant Science
biology.organism_classification
Biochemistry
Anti-inflammatory
Acronychia
Analytical Chemistry
Rutaceae
Downregulation and upregulation
Prenylation
Activity guided fractionation
medicine
No production

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