Back to Search
Start Over
Prevalence and Predictors of Clinically Relevant Atrial High-Rate Episodes in Patients with Cardiac Implantable Electronic Devices
- Source :
- Korean Circulation Journal
- Publication Year :
- 2020
- Publisher :
- The Korean Society of Cardiology, 2020.
-
Abstract
- Background and objectives Atrial high-rate episodes (AHREs) can be continuously detected by cardiovascular implantable electronic devices (CIEDs); however, the predictors of clinically relevant AHREs are unclear. Methods This prospective multicenter study monitored 816 patients (median age 73 years, 40.4% male) without atrial fibrillation (AF) from September 2017 to July 2020. AHREs was defined as a programmed atrial detection rate >220 beats/min. The reference values of 6 minutes and 6 hours were set to analyze clinical implication of AHREs based on previously published data that the 6 minutes excluded most episodes of oversensing. Results During a median follow-up of 18 months (interquartile interval 9-26 months), AHREs with the longest durations of >15 seconds, >6 minutes, and >6 hours and clinically documented AF by electrocardiography were noted in 246 (30.1%), 112 (13.7%), 49 (6.0%), and 24 (2.9%) patients, respectively. Among patients developing AHREs >6 minutes, 102 (91.1%) of 112 patients were identified at the 6-month visit. Patients with AHREs >6 minutes had higher proportions of sick sinus syndrome, subjects with atrial premature beat >1% on Holter monitoring, and larger left atrium (LA) size than patients with AHREs ≤6 minutes. Multivariable logistic regression analysis showed that LA diameter >41 mm (odds ratio [OR], 2.08; 95% confidence interval [95% CI], 1.25-3.45), and sick sinus syndrome (OR, 3.22; 95% CI, 1.91-5.43) were associated with AHREs >6 minutes. Conclusions In patients with LA diameter >41 mm, and sick sinus syndrome before CIEDs implantation is associated with risk of developing AHREs >6 minutes. Trial registration ClinicalTrials.gov Identifier: NCT03303872.
- Subjects :
- medicine.medical_specialty
Left atrium
Sick sinus syndrome
030204 cardiovascular system & hematology
03 medical and health sciences
0302 clinical medicine
Interquartile range
Internal medicine
Internal Medicine
medicine
In patient
030212 general & internal medicine
Original Research
medicine.diagnostic_test
business.industry
Atrial fibrillation
Odds ratio
medicine.disease
Confidence interval
medicine.anatomical_structure
Pacemaker, artificial
Cardiology
Cardiology and Cardiovascular Medicine
business
Electrocardiography
Arrhythmia
Subjects
Details
- Language :
- English
- ISSN :
- 17385555 and 17385520
- Volume :
- 51
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Korean Circulation Journal
- Accession number :
- edsair.doi.dedup.....3000d486cebeba3ff5a380fe50533992