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The impact of Clostridium difficile infection on resource use and costs in hospitals in Spain and Italy: a matched cohort study
The impact of Clostridium difficile infection on resource use and costs in hospitals in Spain and Italy: a matched cohort study
- Source :
- International Journal of Infectious Diseases, Vol 36, Iss C, Pp 31-38 (2015)
- Publication Year :
- 2014
-
Abstract
- Summary Objective To assess the impact of Clostridium difficile infection (CDI) on hospital resources and costs in Spain and Italy. Methods CDI data were collected from institutions in Spain and Italy. Each patient was matched with two randomly selected uninfected controls in the same institution. Patient outcomes were assessed for the first and second episodes of CDI and for patients aged ≤65 and >65 years. The impact of CDI on hospital length of stay (LOS) was used to calculate CDI-attributable costs. A multivariate analysis using duration of stay as the continuous outcome variable assessed the independent effect of CDI on hospital costs and LOS. Results LOS attributable to CDI ranged from 7.6–19.0 days in adults and was 5.0 days in children; the increases were greater in adults in Italy than in Spain. Attributable costs per adult patient ranged from €4396 in Madrid to €14 023 in Rome, with the majority of the cost being due to hospitalization. For children, the total attributable cost was €3545/patient. Conclusions These data show that the burden of CDI is considerable in Spain and Italy. Treatments that can reduce LOS, disease severity, and recurrence rates, as well as effective infection control measures to prevent transmission, have the potential to reduce the burden of CDI.
- Subjects :
- Microbiology (medical)
Adult
Male
Pediatrics
medicine.medical_specialty
Matched cohort analysis
Multivariate analysis
genetic structures
Adolescent
Length of hospitalization
lcsh:Infectious and parasitic diseases
Cost burden
Cohort Studies
Young Adult
Matched cohort
Outcome variable
Disease severity
Clostridium difficile infection
cost
Medicine
Infection control
Humans
lcsh:RC109-216
Hospital Costs
Child
Aged
business.industry
Clostridioides difficile
General Medicine
Clostridium difficile
Length of Stay
Middle Aged
Hospitalization
Infectious Diseases
Italy
Spain
Clostridium Infections
Resource use
Health Resources
epidemiology
Female
CDI
Hospital length of stay
business
Subjects
Details
- ISSN :
- 18783511
- Volume :
- 36
- Database :
- OpenAIRE
- Journal :
- International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
- Accession number :
- edsair.doi.dedup.....2ff8039aa99d5b81ffbd600dc86042a8