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Risk factors affect the survival outcome of hard palatal and maxillary alveolus squamous cell carcinoma: 10-year review in a tertiary referral center
- Source :
- Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 110:11-17
- Publication Year :
- 2010
- Publisher :
- Elsevier BV, 2010.
-
Abstract
- Objective Hard palatal cancer is relatively rare in the head and neck region. Treatment outcome, risk factors that lead to poor survival outcome, and treatment strategy are still controversial. Study design Retrospective study in a tertiary medical center. Results Surgery is a better treatment strategy than concurrent chemoradiation therapy (CCRT) for achieving positive survival outcomes. We also found a higher surgical salvage rate in patients with hard palatal cancer who had local recurrence or neck relapse. Soft palate or infratemporal fossa involvement had poor outcomes. Ulcerative tumor features, tumor volumes larger than 10 mL, and local recurrent tumors that could not undergo salvage surgery also had poorer survival outcomes in our study. Conclusion Surgical management is still the first choice for patients with hard palate or alveolus squamous cell carcinomas even when patients had local or neck regional recurrence.
- Subjects :
- Palate, Hard
Reoperation
medicine.medical_specialty
Antineoplastic Agents
Disease-Free Survival
Risk Factors
Alveolar Process
Humans
Medicine
Neoplasm Invasiveness
Basal cell carcinoma
Risk factor
General Dentistry
Neoplasm Staging
Retrospective Studies
Maxillary Neoplasms
Salvage Therapy
Palatal Neoplasms
Soft palate
business.industry
Infratemporal fossa
Temporal Bone
Cancer
Radiotherapy Dosage
Retrospective cohort study
Middle Aged
medicine.disease
Neoadjuvant Therapy
Surgery
Survival Rate
Treatment Outcome
medicine.anatomical_structure
Otorhinolaryngology
Epidermoid carcinoma
Chemotherapy, Adjuvant
Carcinoma, Squamous Cell
Neck Dissection
Radiotherapy, Adjuvant
Hard palate
Cisplatin
Neoplasm Recurrence, Local
Palate, Soft
Oral Surgery
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 10792104
- Volume :
- 110
- Database :
- OpenAIRE
- Journal :
- Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology
- Accession number :
- edsair.doi.dedup.....2fb623d2824331bfd0d1546293283c9f