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Magnetic Iron Oxide Nanoparticles: Synthesis, Characterization and Functionalization for Biomedical Applications in the Central Nervous System
- Source :
- Materials, Materials, Vol 12, Iss 3, p 465 (2019)
- Publication Year :
- 2019
- Publisher :
- MDPI, 2019.
-
Abstract
- Magnetic Nanoparticles (MNPs) are of great interest in biomedicine, due to their wide range of applications. During recent years, one of the most challenging goals is the development of new strategies to finely tune the unique properties of MNPs, in order to improve their effectiveness in the biomedical field. This review provides an up-to-date overview of the methods of synthesis and functionalization of MNPs focusing on Iron Oxide Nanoparticles (IONPs). Firstly, synthesis strategies for fabricating IONPs of different composition, sizes, shapes, and structures are outlined. We describe the close link between physicochemical properties and magnetic characterization, essential to developing innovative and powerful magnetic-driven nanocarriers. In conclusion, we provide a complete background of IONPs functionalization, safety, and applications for the treatment of Central Nervous System disorders.
- Subjects :
- biomedical applications
magnetic nanoparticles
Materials science
synthesis
Nanotechnology
02 engineering and technology
Review
010402 general chemistry
01 natural sciences
lcsh:Technology
chemistry.chemical_compound
General Materials Science
lcsh:Microscopy
lcsh:QC120-168.85
Biomedical applications
Central nervous system
Iron oxide nanoparticles
Magnetic nanoparticles
Synthesis
lcsh:QH201-278.5
lcsh:T
iron oxide nanoparticles
021001 nanoscience & nanotechnology
central nervous system
0104 chemical sciences
Characterization (materials science)
chemistry
lcsh:TA1-2040
Surface modification
lcsh:Descriptive and experimental mechanics
lcsh:Electrical engineering. Electronics. Nuclear engineering
Nanocarriers
0210 nano-technology
lcsh:Engineering (General). Civil engineering (General)
lcsh:TK1-9971
Subjects
Details
- Language :
- English
- ISSN :
- 19961944
- Volume :
- 12
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Materials
- Accession number :
- edsair.doi.dedup.....2f97705b967491af724d540e469bca75