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Recent Asian origin of chytrid fungi causing global amphibian declines
- Source :
- Science, Digital.CSIC. Repositorio Institucional del CSIC, instname
- Publication Year :
- 2020
- Publisher :
- American Association for the Advancement of Science, 2020.
-
Abstract
- Globalized infectious diseases are causing species declines worldwide, but their source often remains elusive. We used whole-genome sequencing to solve the spatiotemporal origins of the most devastating panzootic to date, caused by the fungus Batrachochytrium dendrobatidis, a proximate driver of global amphibian declines. We traced the source of B. dendrobatidis to the Korean peninsula, where one lineage, BdASIA-1, exhibits the genetic hallmarks of an ancestral population that seeded the panzootic. We date the emergence of this pathogen to the early 20th century, coinciding with the global expansion of commercial trade in amphibians, and we show that intercontinental transmission is ongoing. Our findings point to East Asia as a geographic hotspot for B. dendrobatidis biodiversity and the original source of these lineages that now parasitize amphibians worldwide.<br />S.J.O., T.W.J.G., L.Br., A.Lo., A.A.C., D.S.S., E.A.C., C.M., J.B., D.M.A., F.C., and M.C.F. were supported through NERC (standard grant NE/K014455/1). S.J.O. acknowledges a Microsoft Azure for Research Sponsorship (subscription ID: ab7cd695-49cf-4a83-910a-ef71603e708b). T.W.J.G., A.Lo., A.A.C., D.S.S., E.A.C., C.M., J.B., D.M.A., F.C., and M.C.F. were also supported by the EU BiodivERsA scheme (RACE, funded through NERC directed grant NE/G002193/1 and ANR08-Biodiversa-002-03) and NERC (standard grant NE/K012509/1). M.C.F., E.A.C., and C.M. acknowledge the Nouragues Travel Grant Program 2014. R.A.F. was supported by an MIT/Wellcome Trust Fellowship. T.W.J.G. was supported by the People’s Trust for Endangered Species and the Morris Animal Foundation (D12ZO002). J.M.G.S. and M.C.F. were supported by the Leverhulme Trust (RPG-2014-273) and the Morris Animal Foundation (D16ZO-022). F.B. was supported by the ERC (grant ERC 260801–Big_Idea). D.M.A. was funded by Wellcome Trust grant 099202. J.V. was supported by the Hungarian Scientific Research Fund (OTKA K77841) and Bolyai János Research Scholarship, Hungarian Academy of Sciences (BO/00579/14/8). D.J.G. was supported by the Conservation Leadership Programme (grant 0134010) with additional assistance from F. Gebresenbet, R. Kassahun, and S. P. Loader. C.S.-A. was supported by Fondecyt Nº11140902 and 1181758. T.M.D.-B. was supported by the Royal Geographical Society and the Royal Zoological Society of Scotland with assistance from M. Hirschfeld and the Budongo Conservation Field Station. B.W. was supported by the National Research Foundation of Korea (2015R1D1A1A01057282). L.F.T. was supported by FAPESP (#2016/25358-3) and CNPq (#300896/2016-6). L.Be., L.F.S., and R.J.W. were supported by the Australian Research Council (FT100100375, DP120100811). A.A.C. was supported by a Royal Society Wolfson Research Merit award. J.H., A.La., and S.M. were funded by the Swedish Research Council Formas (grant no. 2013- 1389-26445-20). C.W. was funded by the National Research Foundation, South Africa. T.Y.J. and T.S.J. acknowledge NSF grant DEB-1601259. W.E.H. was funded by the NSERC Strategic and Discovery grant programs
- Subjects :
- 0106 biological sciences
0301 basic medicine
DYNAMICS
Batrachochytrium salamandrivorans
Biodiversity
L73 - Maladies des animaux
01 natural sciences
DISEASE
EMERGENCE
BATRACHOCHYTRIUM-DENDROBATIDIS
HISTORY
Phylogeny
2. Zero hunger
education.field_of_study
Multidisciplinary
biology
Virulence
Ecology
Multidisciplinary Sciences
Europe
medicine.drug_formulation_ingredient
EXTINCTION
Chytridiomycota
Emerging infectious disease
Science & Technology - Other Topics
Amphibian
Asia
General Science & Technology
Population
Genes, Fungal
Extinction, Biological
010603 evolutionary biology
INTERNATIONAL-TRADE
Article
Amphibians
03 medical and health sciences
biology.animal
medicine
genomics
Animals
Chytridiomycosis
education
CHYTRIDIOMYCOSIS
Panzootic
PATHOGENS
Science & Technology
Korea
LINEAGES
Australia
Genetic Variation
Sequence Analysis, DNA
15. Life on land
biology.organism_classification
030104 developmental biology
Africa
M40 - Écologie aquatique
Hybridization, Genetic
Americas
Subjects
Details
- Language :
- English
- ISSN :
- 00368075
- Database :
- OpenAIRE
- Journal :
- Science, Digital.CSIC. Repositorio Institucional del CSIC, instname
- Accession number :
- edsair.doi.dedup.....2f7cec66a08c8458bc387bc4b7b83134