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Diffuse scleroderma occurring after the use of paclitaxel for ovarian cancer
- Source :
- Clinical Rheumatology. 22:49-52
- Publication Year :
- 2003
- Publisher :
- Springer Science and Business Media LLC, 2003.
-
Abstract
- A case of diffuse scleroderma in a 56-year-old woman who received paclitaxel for the treatment of a metastatic ovarian cancer is presented. The clinical cutaneous alterations, as well as the capillaroscopic and histological findings, were indistinguishable from those encountered in definite systemic sclerosis (SSc). In contrast to SSc, Raynaud's phenomenon and cutaneous calcinosis were absent and antinuclear antibodies were negative. The temporal relationship between the onset of skin involvement and administration of the drug may indicate an effect of paclitaxel.
- Subjects :
- medicine.medical_specialty
Pathology
Paclitaxel
Anti-nuclear antibody
Scleroderma
chemistry.chemical_compound
Rheumatology
Calcinosis
Internal medicine
Humans
Medicine
skin and connective tissue diseases
Skin
Ovarian Neoplasms
Scleroderma, Systemic
integumentary system
business.industry
General Medicine
Middle Aged
medicine.disease
Antineoplastic Agents, Phytogenic
Dermatology
Capillaries
Diffuse scleroderma
chemistry
Female
business
Ovarian cancer
Metastatic ovarian cancer
Subjects
Details
- ISSN :
- 14349949 and 07703198
- Volume :
- 22
- Database :
- OpenAIRE
- Journal :
- Clinical Rheumatology
- Accession number :
- edsair.doi.dedup.....2f43f3cedc17b1b778455d67ed0dceee