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Six-month outcomes and effect of pulmonary rehabilitation among patients hospitalized with COVID-19: a retrospective cohort study
- Source :
- Annals of Medicine, article-version (VoR) Version of Record
- Publication Year :
- 2021
- Publisher :
- Informa UK Limited, 2021.
-
Abstract
- Background Patients appear to maintain sequelae post-coronavirus disease 2019 (COVID-19) affecting daily life and physical health. We investigated the changes in and the effects of pulmonary rehabilitation (PR) on exercise capacity and immunology six months after COVID-19 hospitalization. Methods This retrospective cohort reviewed 233 COVID-19 patients admitted from 17 January 2020 to 29 February 2020. Ninety-eight patients who completed 2-week and 6-month follow-ups and tests were included. Among 98 patients, 27 completed at least five sessions of PR at the First Hospital of Changsha, China, during the 6-month convalescence were allocated to the PR group; the reminder who had not performed any PR were assigned to the control group. The primary outcome was the change in six-minute walk distance (6-MWD) between the 2-week and 6-month follow-ups, which was assessed via analysis of covariance with a covariate of propensity score that adjusted for the potential confounders. Secondary outcomes were the changes in 6-MWD, SARS-CoV-2 immunoglobulins, T-lymphocytes and blood chemistry, which were evaluated via paired tests. Results Participants’ ages ranged from 19 to 84 years (M = 47, standard deviation (SD)=15) 45.9% identified as male. During the 6-month convalescence, 6-MWD increased 27.0%, with a mean [95% CI] of 113 [92–134] m (p
- Subjects :
- Adult
Male
medicine.medical_specialty
Physical Medicine & Rehabilitation
Coronavirus disease 2019 (COVID-19)
medicine.medical_treatment
media_common.quotation_subject
rehabilitation
Young Adult
Internal medicine
medicine
Humans
Pulmonary rehabilitation
Aged
Retrospective Studies
media_common
Aged, 80 and over
Rehabilitation
exercise
SARS-CoV-2
business.industry
Convalescence
Confounding
COVID-19
Retrospective cohort study
General Medicine
Middle Aged
immunity
Hospitalization
Blood chemistry
Propensity score matching
Quality of Life
biomarker
business
respiration
Research Article
Subjects
Details
- ISSN :
- 13652060 and 07853890
- Volume :
- 53
- Database :
- OpenAIRE
- Journal :
- Annals of Medicine
- Accession number :
- edsair.doi.dedup.....2f3be654ee7418405a7cc3bef9165503