Gut Microbiome Modulation by Antibiotics in Adult Asthma: A Human Proof-of-Concept Intervention Trial

Authors :: Tjitske S.R. Van Engelen
Jack Yang
Bastiaan W. Haak
Peter I. Bonta
Tom Van Der Poll
W. Joost Wiersinga
Tjitske S.R. van Engelen
Floor Hugenholtz
Christof J. Majoor
Cornelis van ‘t Veer
E. Marleen Kemper
Elisabeth H. Bel
Tom van der Poll
Center of Experimental and Molecular Medicine
Graduate School
AII - Infectious diseases
Pulmonology
ACS - Pulmonary hypertension & thrombosis
Infectious diseases
Source :: Clinical gastroenterology and hepatology. W.B. Saunders Ltd
Publication Year :: 2022
Publisher :: Elsevier BV, 2022.
Abstract: Although the pathophysiology of asthma is complex, perturbation of the gut microbiota has been associated with an increased risk of asthma development in childhood.1 Disruption and subsequent dysregulation of gut microbiota-related immunologic processes have also been linked to disease severity and response to treatment.2.

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