Back to Search
Start Over
Extracorporeal life support in mitral papillary muscle rupture: Outcome of multicenter study
- Source :
- Artificial Organs.
- Publication Year :
- 2023
-
Abstract
- BACKGROUND: Post-acute myocardial infarction papillary muscle rupture (post-AMI PMR) may present variable clinical scenarios and degree of emergency due to result of cardiogenic shock. Veno-arterial extracorporeal life support (V-A ECLS) has been proposed to improve extremely poor pre- or postoperative conditions. Information in this respect is scarce. METHODS: From the CAUTION (meChanical complicAtion of acUte myocardial infarcTion: an InternatiOnal multiceNter cohort study) database (16 different Centers, data from 2001 to 2018), we extracted adult patients who were surgically treated for post-AMI PMR and underwent pre- or/and postoperative V-A ECLS support. The end-points of this study were in-hospital survival and ECLS complications. RESULTS: From a total of 214 post-AMI PMR patients submitted to surgery, V-A ECLS was instituted in 23 (11%) patients. The median age was 61.7 years (range 46-81 years). Preoperatively, ECLS was commenced in 10 patients (43.5%), whereas intra/postoperative in the remaining 13. The most common V-A ECLS indication was post-cardiotomy shock, followed by preoperative cardiogenic shock and cardiac arrest. The median duration of V-A ECLS was 4 days. V-A ECLS complications occurred in more than half of the patients. Overall, in-hospital mortality was 39.2% (9/23), compared to 22% (42/219) for the non-ECLS group. CONCLUSIONS: In post-AMI PMR patients, V-A ECLS was used in almost 10% of the patients either to promote bridge to surgery or as postoperative support. Further investigations are required to better evaluate a potential for increased use and its effects of V-A ECLS in such a context based on the still high perioperative mortality. ispartof: ARTIFICIAL ORGANS ispartof: location:United States status: Published online
- Subjects :
- Technology
Transplantation
Science & Technology
SURGERY
MEMBRANE-OXYGENATION
Biomedical Engineering
Medizin
Medicine (miscellaneous)
acute myocardial infarction
Bioengineering
MECHANICAL COMPLICATIONS
General Medicine
BRIDGE
Biomaterials
papillary muscle rupture
Engineering
SURGICAL-TREATMENT
mitral regurgitation
Life Sciences & Biomedicine
Engineering, Biomedical
Subjects
Details
- Language :
- English
- ISSN :
- 0160564X
- Database :
- OpenAIRE
- Journal :
- Artificial Organs
- Accession number :
- edsair.doi.dedup.....2f14183568273c45eb9f375175ab8cd2