Three-dimensional imaging for diagnostic ultrasound in dermatology

Background : Visual examination and cutaneous biopsies, two major tools in dermatologie diagnosis, do not provide structural information regarding the entire tissue volume. Objective : Our purpose was to develop a high-resolution ultrasound system that quickly, with minimal operator interaction, displays structural data on the entire tissue volume. Methods : A prototype ultrasound B-scan system was developed and operated at nominal center frequencies between 35 and 50 MHz, with computer processing of data to produce three-dimensional images. These images displayed as three-dimensional "blocks" can be sectioned to provide multiple images of internal structure (i.e., "acoustic biopsies"). Results : B-scans and associated three-dimensional images were obtained from assorted skin sites in selected patients. Conclusion : This technique provides a valuable diagnostic tool that is now being further evaluated.