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Frequency of serovars and antimicrobial resistance in Shigella spp. from Brazil
- Source :
- Memórias do Instituto Oswaldo Cruz., Vol 101, Iss 3, Pp 245-250 (2006), Memórias do Instituto Oswaldo Cruz, Volume: 101, Issue: 3, Pages: 245-250, Published: MAY 2006
- Publication Year :
- 2006
- Publisher :
- Instituto Oswaldo Cruz, Ministério da Saúde, 2006.
-
Abstract
- A total of 296 Shigella spp. were received from State Public Health Laboratories, during the period from 1999 to 2004, by National Reference Laboratory for Cholera and Enteric Diseases (NRLCED) - IOC/Fiocruz, Rio de Janeiro, Brazil. The frequency of Shigella spp. was: S. flexneri (52.7%), S. sonnei (44.2%), S. boydii (2.3%), and S. dysenteriae (0.6%). The most frequent S. flexneri serovars were 2a and 1b. The highest incidence rates of Shigella isolation were observed in the Southeast (39%) and Northeast (34%) regions and the lowest rate in the South (3%) of Brazil. Strains were further analyzed for antimicrobial susceptibility by disk diffusion method as part of a surveillance program on antimicrobial resistance. The highest rates of antimicrobial resistance were to trimethoprim-sulfamethozaxole (90%), tetracycline (88%), ampicillin (56%), and chloramphenicol (35%). The patterns of antimicrobial resistance among Shigella isolates pose a major difficulty in the determination of an appropriate drug for shigellosis treatment. Continuous monitoring of antimicrobial susceptibilities of Shigella spp. through a surveillance system is thus essential for effective therapy and control measures against shigellosis.
- Subjects :
- Microbiology (medical)
Serotype
Shigellosis
lcsh:Arctic medicine. Tropical medicine
lcsh:RC955-962
lcsh:QR1-502
Microbial Sensitivity Tests
Drug resistance
Biology
medicine.disease_cause
serovars
lcsh:Microbiology
Microbiology
Antibiotic resistance
antimicrobial resistance surveillance
Ampicillin
Drug Resistance, Bacterial
Prevalence
medicine
Humans
Shigella
Serotyping
medicine.disease
Antimicrobial
Cholera
Anti-Bacterial Agents
Brazil
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 16788060 and 00740276
- Volume :
- 101
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Memórias do Instituto Oswaldo Cruz.
- Accession number :
- edsair.doi.dedup.....2eaeb49c40b2501beabee89f144667b3