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Review of the Traditional Uses, Phytochemistry, and Pharmacological Activities of Rhoicissus Species (Vitaceae)
- Source :
- Molecules, Vol 26, Iss 2306, p 2306 (2021), Molecules
- Publication Year :
- 2021
- Publisher :
- MDPI AG, 2021.
-
Abstract
- Species within the genus Rhoicissus (Vitaceae) are commonly used in South African traditional medicine. The current review discusses the occurrence, distribution, traditional uses, phytochemistry, and pharmacological properties of Rhoicissus species covering the period 1981–2020. The data reported were systematically collected, read, and analysed from scientific electronic databases including Scopus, Scifinder, Pubmed, and Google Scholar. Reported evidence indicates that species in this genus are used for the treatment of gastrointestinal complaints, sexually transmitted infections (STIs), and infertility, as well as to tone the uterus during pregnancy and to facilitate delivery. Pharmacological studies have further shown that members of the Rhoicissus genus display antidiabetic, uterotonic, ascaricidal, hepatoprotective, antioxidant, antimicrobial, anticancer, and anti-inflammatory properties. They are linked to the presence of bioactive compounds isolated from the genus. Hence, Rhoicissus species can potentially be an alternative therapeutic strategy to treat diseases and develop safer and more potent drugs to combat diseases. Plant species of this genus have valuable medicinal benefits due to their significant pharmacological potential. However, scientific investigation and information of the therapeutic potential of Rhoicissus remain limited as most of the species in the genus have not been fully exploited. Therefore, there is a need for further investigations to exploit the therapeutic potential of the genus Rhoicissus. Future studies should evaluate the phytochemical, pharmacological, and toxicological activities, as well as the mode of action, of Rhoicissus crude extracts and secondary compounds isolated from the species.
- Subjects :
- 0106 biological sciences
Phytochemistry
Rhoicissus
Phytochemicals
Pharmaceutical Science
Organic chemistry
Review
Biology
Vitaceae
010603 evolutionary biology
01 natural sciences
Antioxidants
Analytical Chemistry
QD241-441
Genus
Drug Discovery
Animals
Humans
Physical and Theoretical Chemistry
Therapeutic strategy
cuneifolia
Traditional medicine
Plant Extracts
botany
biology.organism_classification
0104 chemical sciences
010404 medicinal & biomolecular chemistry
Phytochemical
Chemistry (miscellaneous)
Plant species
Molecular Medicine
phytochemistry
African traditional medicine
Medicine, Traditional
pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 14203049
- Volume :
- 26
- Issue :
- 2306
- Database :
- OpenAIRE
- Journal :
- Molecules
- Accession number :
- edsair.doi.dedup.....2e8de8ba6ce1ea8bed348688a762da06