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Intracerebroventricular administration of bombesin inhibits biliary and gastric secretion in the rat
- Source :
- Journal of neuroscience research. 22(4)
- Publication Year :
- 1989
-
Abstract
- The effect of intracerebroventricular (ICV) bombesin on bile and gastric acid secretion was examined in the rat. ICV bombesin (10 micrograms in 10 microliters) inhibited basal biliary volume by 27% and bile bicarbonate by 52% of control values, while gastric acid secretion was decreased by 75%. These results provide evidence for central mechanisms for the control of gastrointestinal function.
- Subjects :
- Male
medicine.medical_specialty
Bicarbonate
Biology
complex mixtures
digestive system
Cerebral Ventricles
Gastric Acid
Cellular and Molecular Neuroscience
chemistry.chemical_compound
Basal (phylogenetics)
Reference Values
Internal medicine
medicine
Animals
Bile
Secretion
Injections, Intraventricular
Gastric Juice
digestive, oral, and skin physiology
Bombesin
Rats, Inbred Strains
Gastric secretion
Rats
Kinetics
Endocrinology
chemistry
Gastric acid
Gastrointestinal function
hormones, hormone substitutes, and hormone antagonists
Gastric acid output
Subjects
Details
- ISSN :
- 03604012
- Volume :
- 22
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Journal of neuroscience research
- Accession number :
- edsair.doi.dedup.....2e25dd7bcaa0f1605fad6a52995e6789