Back to Search
Start Over
The risk of endothelial and erectile dysfunctions in Behçet’s disease: a comparative analysis of mucocutaneous and systemic patient groups
- Source :
- Advances in Dermatology and Allergology, Vol 38, Iss 4, Pp 622-628 (2021), Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii
- Publication Year :
- 2021
- Publisher :
- Termedia Sp. z.o.o., 2021.
-
Abstract
- Introduction Behçet’s disease (BD) is a chronic inflammatory disease which can be limited to only mucocutaneous tissues or can affect different systems of the body. Aim To investigate the association of endothelial and erectile dysfunctions with BD, on the basis of comparative analysis between mucocutaneous and systemic BD. Material and methods Thirty-eight men diagnosed with BD were included in the present study. The patients were stratified into two groups as mucocutaneous BD (n = 20, MBD group), and systemic BD (n = 18, SBD group). Erectile dysfunction (ED) was assessed using the Erectile Function domain of the International Index of Erectile Function (IIEF-EF) questionnaire. The coronary flow reserve (CFR) assessment was done for analysing endothelial dysfunction (EnD), and CFR < 2 was defined as EnD. Penile Doppler ultrasonography (PDU) was performed for ED. The demographic and clinical parameters, IIEF-EF score ED classification, CFR and PDU test findings were compared between two groups. Results The median age was 34 (22–52) years in the overall population, and there was no difference between two groups (p = 0.558). Time from diagnosis was significantly longer (24 vs. 102 months, p = 0.021) and the use of immunosuppressive therapies was higher (0 vs. 70.6%, p < 0.001) in the SBD group. In overall, median CFR was 1.92 (1.1–5.96), and there was no difference between two groups (1.88 vs. 1.97, p = 0.812). The percentage of patients with CFR < 2 was similar in two groups (52.6% vs. 52.9%, p = 0.985). The ED status according to IIEF-EF was similar in two groups (45% vs. 27.8%, p = 0.538) as well as according to PDU analyses (10% vs. 16.7%, p = 0.544). Conclusions The increased risk of endothelial, and erectile dysfunctions should be considered in men who were diagnosed with mucocutaneous and systemic BD.
- Subjects :
- medicine.medical_specialty
mucocutaneous
erectile dysfunction
Mucocutaneous zone
Population
Dermatology
Behcet's disease
Disease
behçet’s disease
Gastroenterology
endothelial dysfunction
Internal medicine
medicine
Immunology and Allergy
Endothelial dysfunction
systemic
education
Original Paper
education.field_of_study
business.industry
Coronary flow reserve
medicine.disease
RC31-1245
Increased risk
Erectile dysfunction
RL1-803
business
Subjects
Details
- ISSN :
- 1642395X
- Volume :
- 38
- Database :
- OpenAIRE
- Journal :
- Advances in Dermatology and Allergology
- Accession number :
- edsair.doi.dedup.....2e24b6fc36346b95cd0bd6f3c0693a10