Synthesis and Anti-Platelet Activity of Thiosulfonate Derivatives Containing a Quinone Moiety

Authors :: Patrice Vanelle
Khrystyna Bolibrukh
Vira Lubenets
Volodymyr Novikov
Thierry Terme
Svyatoslav Polovkovych
T. I. Halenova
Irina Nikolaeva
Omar Khoumeri
Olexiy Savchuk
Institut de Chimie Radicalaire (ICR)
Aix Marseille Université (AMU)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
Source :: Scientia Pharmaceutica, Scientia Pharmaceutica, 2015, 83 (2), pp.221--231. ⟨10.3797/scipharm.1411-14⟩, Volume 83, Issue 2, Pages 221-231
Publication Year :: 2014
Abstract: International audience; Thiosulfonate derivatives based on quinones were synthesized for studying "structure-activity relationship" compounds with an acylated and a free amino-group. Anti-platelet activity of the synthesized compounds was determined and the influence of substituents on the activity of the derivatives was assessed.

Subjects :: Anti-platelet activity
Chemistry
Stereochemistry
Thiosulfonate
Pharmaceutical Science
Moiety
[CHIM]Chemical Sciences
Quinone
Anti platelet
Research Article

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