Back to Search
Start Over
Graphene quantum dot electrochemiluminescence increase by bio-generated H2O2 and its application in direct biosensing
- Source :
- Royal Society Open Science, Royal Society Open Science, Vol 7, Iss 1 (2020)
- Publication Year :
- 2020
- Publisher :
- The Royal Society, 2020.
-
Abstract
- In this study, a novel signal-increase electrochemiluminescence (ECL) biosensor has been developed for the detection of glucose based on graphene quantum dot/glucose oxidase (GQD/GO x ) on Ti foil. The proposed GQD with excellent ECL ability is synthesized through a green one-step strategy by the electrochemical reduction of graphene oxide quantum dot. Upon the addition of glucose, GO x can catalytically oxidize glucose and the direct electron transfer between the redox centre of GO x and the modified electrode also has been realized, which results in the bio-generated H 2 O 2 for ECL signal increase in GQD and realizes the direct ECL detection of glucose. The signal-increase ECL biosensor enables glucose detection with high sensitivity reaching 5 × 10 −6 mol l −1 in a wide linear range from 5 × 10 −6 to 1.5 × 10 −3 mol l −1 . Additionally, the fabrication process of such GQD-based ECL biosensor is also suitable to other biologically produced H 2 O 2 system, suggesting the possible applications in the sensitive detection of other biologically important targets (e.g. small molecules, protein, DNA and so on).
- Subjects :
- endocrine system
Materials science
graphene quantum dot
Nanotechnology
02 engineering and technology
010402 general chemistry
biosensor
01 natural sciences
Electrochemiluminescence
Glucose oxidase
direct electron transfer
glucose
lcsh:Science
FOIL method
Multidisciplinary
biology
021001 nanoscience & nanotechnology
Graphene quantum dot
glucose oxidase
0104 chemical sciences
Chemistry
biology.protein
lcsh:Q
0210 nano-technology
Biosensor
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 20545703
- Volume :
- 7
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Royal Society Open Science
- Accession number :
- edsair.doi.dedup.....2de34f6c7ffa5f1f27190c0e87e93761