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Comparison of the Effects of Bitter Melon (Momordica charantia) and Gotu Kola (Centella asiatica) Extracts on Healing of Open Wounds in Rabbits
- Source :
- Kafkas Universitesi Veteriner Fakultesi Dergisi.
- Publication Year :
- 2013
- Publisher :
- Kafkas University, 2013.
-
Abstract
- This study investigated the effects of topically applied oily homogenized and powder forms of bitter melon (Momordica charantia) (MC) and ointment formulation of gotu kola (Centella asiatica) (CA) extract and compared the results with untreated control and pure olive oil groups on wound healing in rabbits. A total of 30 New Zealand rabbits were divided into five equal groups (oily homogenized form of MC, powder form of MC, ointment of CA, control, pure olive oil). Full-thickness 5x5 cm skin wounds were created on the right mid-dorsum area and experimental groups were treated daily with the above mentioned extracts. Wounds were observed daily. Planimetry was performed for the unhealed wound area and the percentage of total wound healing on days 0, 7, 14, 21 and 28. Median time for the first observable granulation tissue was shorter in all experimental groups than in the control group (P
- Subjects :
- Veterinary sciences
Centella asiatica
Momordica charantia
Open wounds
Wound healing
Titrated extract
Clinical profile
Yara iyileşmesi
Rabbit
Momordica Charantia
Cucurbitane
Extract
Fruits
Inhibition
Centella
General Veterinary
Momordica
biology
Traditional medicine
Modern phytomedicine
Proteins
Bitter melon
Tavşan
biology.organism_classification
Rats
Cucurbitaceae
Seeds
Gourd
Subjects
Details
- ISSN :
- 13006045
- Database :
- OpenAIRE
- Journal :
- Kafkas Universitesi Veteriner Fakultesi Dergisi
- Accession number :
- edsair.doi.dedup.....2cee907df42c82ba8230825c09ebe2f7