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Late-onset Circulatory Collapse and Continuous Positive Airway Pressure are Useful Predictors of Treatment-requiring Retinopathy of Prematurity: A 9-year Retrospective Analysis
- Source :
- Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017), Scientific Reports
- Publication Year :
- 2017
- Publisher :
- Springer Science and Business Media LLC, 2017.
-
Abstract
- sVisual loss caused by retinopathy of prematurity (ROP) will be prevented if treatment-requiring ROP (TR-ROP) can be predicted. In this retrospective study including 418 infants with ≤32 weeks of gestational age (GA) and/or ≤1500 grams of birthweight, we attempted to identify useful predictors. We also examined the efficiency of significant predictors compared with existing predictive models, ROPScore and CHOP model. Multivariable logistic regression analyses supported the following factors were useful for predicting TR-ROP from all infants and infants with any ROP: GA (odds ratio [OR], 0.47 and 0.48), history of late-onset circulatory collapse (LCC) (OR, 2.76 and 2.44) and use of continuous positive airway pressure (CPAP) at 35 weeks of postmenstrual age (OR, 3.78 and 4.50). The comparison of areas under receiver operating characteristic curves indicated the combination of LCC, CPAP and ROPScore was better than ROPScore to predict TR-ROP from all infants and infants with any ROP (P = 0.007 and 0.02) and the combination of LCC, CPAP and CHOP model was also better than CHOP model to predict TR-ROP from all infants and infants with any ROP (P = 0.01 and 0.02). Our results suggested infants with a history of LCC and a long CPAP support have a high incidence of TR-ROP.
- Subjects :
- Male
congenital, hereditary, and neonatal diseases and abnormalities
Pediatrics
medicine.medical_specialty
Circulatory collapse
genetic structures
Science
medicine.medical_treatment
Blindness
Logistic regression
Article
03 medical and health sciences
0302 clinical medicine
030225 pediatrics
Odds Ratio
medicine
Humans
Retinopathy of Prematurity
Continuous positive airway pressure
Retrospective Studies
Multidisciplinary
Continuous Positive Airway Pressure
business.industry
Infant, Newborn
Postmenstrual Age
Infant
Gestational age
Shock
Retrospective cohort study
Retinopathy of prematurity
Odds ratio
Prognosis
medicine.disease
eye diseases
ROC Curve
Area Under Curve
030221 ophthalmology & optometry
Medicine
Female
business
Subjects
Details
- ISSN :
- 20452322
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....2cdb85a3a9c73627872663b3579c31cb