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Correction to: Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific association for the study of the liver (APASL): an update

Correction to: Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific association for the study of the liver (APASL): an update

Authors :
Abhijit Chowdhury
Pratibha Kale
Cosmas Rinaldi A Lesmana
Vikrant Sood
Eileen L Yoon
Dharmesh Kapoor
Qin Ning
Cyriac Abby Philips
Ashok Choudhury
Samir Shah
Neeraj Saraf
Barjesh Chander Sharma
Rino Alvani Gani
Subash Gupta
Archana Rastogi
P N Rao
Madunil A. Niriella
Hai Li
Kemal Fariz Kalista
Vinod Arora
Shalimar
Chundamannil E. Eapen
Chetan Kalal
Dong Joon Kim
Hasmik Ghazinyan
Guresh Kumar
Vandana Midha
B. R. Thapa
Anil Arora
Ajit Sood
Anshu Srivastava
Khin Maung Win
Ke Ma
Edward Gane
Wasim Jafri
Ajay Duseja
Ashok Kumar
Harshad Devarbhavi
Sudhir Maharashi
Zeeshan Ahmad Wani
Madhumita Premkumar
V Rajan
Xiaolong Qi
Virender Singh
Mamun Al Mahtab
Gamal Shiha
Akash Shukla
Rajeev Khanna
Diana A. Payawal
Laurentius A. Lesmana
Vivek Vij
Amna Subhan Butt
Samba Siva Rao Pasupuleti
Sanjiv Saigal
Kaushal Madan
Jinhua Hu
Hitendra Garg
Guan H Lee
G Carpio
Viniyendra Pamecha
Mohd Rela
Do Seon Song
Amit Rastogi
R. K. Dhiman
Surender Kumar Yachha
A Olithselvan
Chhagan Bihari Sharma
Atsushi Tanaka
Anoop Saraya
Omesh Goyal
Rajan P Mathur
Jose D. Sollano
Man-Fung Yuen
Zaigham Abbas
A. Kadir Dokmeci
Zhongping Duan
Jin Mo Yang
Yogesh Chawla
Ashish Goel
Shahinul Alam
Rakhi Maiwall
Manoj K Sharma
Lovkesh Anand
Manav Wadhawan
Fazal Karim
Soek Siam Tan
Puja Sakhuja
Vivek A. Saraswat
Osamu Yokosuka
Vishal Garg
Ankur Jindal
Tanmay Vyas
Tao Chen
Sunil Taneja
Seema Alam
Dominic Ray Chaudhuri
Priyanka Jain
Bikrant Bihari Lal
Salimur Rahman
Satoshi Mochida
Meenu Bajpai
Seng Gee Lim
Ananta Shresta
Manoj Sahu
Sombat Treeprasertsuk
Chen Yu
Shiv Kumar Sarin
V G Mohan Prasad
Arvinder S. Soin
Wei Ting Chen
G K Lau
Saeed Hamid
Source :
Hepatology International
Publication Year :
2019
Publisher :
Springer India, 2019.

Abstract

The first consensus report of the working party of the Asian Pacific Association for the Study of the Liver (APASL) set up in 2004 on acute-on-chronic liver failure (ACLF) was published in 2009. With international groups volunteering to join, the “APASL ACLF Research Consortium (AARC)” was formed in 2012, which continued to collect prospective ACLF patient data. Based on the prospective data analysis of nearly 1400 patients, the AARC consensus was published in 2014. In the past nearly four-and-a-half years, the AARC database has been enriched to about 5200 cases by major hepatology centers across Asia. The data published during the interim period were carefully analyzed and areas of contention and new developments in the field of ACLF were prioritized in a systematic manner. The AARC database was also approached for answering some of the issues where published data were limited, such as liver failure grading, its impact on the ‘Golden Therapeutic Window’, extrahepatic organ dysfunction and failure, development of sepsis, distinctive features of acute decompensation from ACLF and pediatric ACLF and the issues were analyzed. These initiatives concluded in a two-day meeting in October 2018 at New Delhi with finalization of the new AARC consensus. Only those statements, which were based on evidence using the Grade System and were unanimously recommended, were accepted. Finalized statements were again circulated to all the experts and subsequently presented at the AARC investigators meeting at the AASLD in November 2018. The suggestions from the experts were used to revise and finalize the consensus. After detailed deliberations and data analysis, the original definition of ACLF was found to withstand the test of time and be able to identify a homogenous group of patients presenting with liver failure. New management options including the algorithms for the management of coagulation disorders, renal replacement therapy, sepsis, variceal bleed, antivirals and criteria for liver transplantation for ACLF patients were proposed. The final consensus statements along with the relevant background information and areas requiring future studies are presented here.<br />Article Highlights Updated on the basis of AARC data of >3300 cases enrolled into AARC registry prospectivelyACLF is distinct form Acute Decompensation of cirrhosisNewer sections on DILI-ACLF, AIH-ACLF, PVT/HVOTO–ACLFReversibility of Chronic Liver Disease in ACLFPortal and systemic hemodynamics and their relevance in ACLFAcute Portal Hypertension and Variceal progression in ACLFAARC score as a guide for treatment strategies in ACLFACLF in Children-first consensus on pediatric ACLF

Details

Language :
English
ISSN :
19360541 and 19360533
Volume :
13
Issue :
6
Database :
OpenAIRE
Journal :
Hepatology International
Accession number :
edsair.doi.dedup.....2c6d99d9178e6221dac760b73651d2a6