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A Systematic Literature Review of the Epidemiology, Health-Related Quality of Life Impact, and Economic Burden of Immunoglobulin A Nephropathy
- Source :
- Journal of Health Economics and Outcomes Research (2021), Journal of Health Economics and Outcomes Research
- Publication Year :
- 2021
- Publisher :
- The Journal of Health Economics and Outcomes Research, 2021.
-
Abstract
- Introduction: This systematic literature review analyzed published evidence on IgA nephropathy (IgAN), focusing on US epidemiology, health-related quality of life (HRQoL), and economic burden of illness. Methods: Using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, Embase®, MEDLINE®, Cochrane, and Econlit (January 2010 to June 2020) were searched, along with relevant congresses (2017-2020). Results: Of 123 epidemiologic studies selected for data extraction, 24 reported IgAN diagnosis rates ranging from 6.3% to 29.7% among adult and pediatric patients undergoing renal biopsy, with all reported US rates Conclusion: While economic evidence in IgAN remains sparse, management of ESRD is a major cost driver. IgAN is a rare disease where disease progression causes increasing patient burden, underscoring the need for therapies that prevent kidney function decline and HRQoL deterioration while reducing mortality.
- Subjects :
- medicine.medical_specialty
Pediatrics
Computer applications to medicine. Medical informatics
R858-859.7
urologic and male genital diseases
Nephropathy
End stage renal disease
Quality of life
renal biopsy
Epidemiology
medicine
immunoglobulin a nephropathy
Depression (differential diagnoses)
end-stage renal disease
business.industry
Incidence (epidemiology)
Health Policy
Public Health, Environmental and Occupational Health
medicine.disease
Nephrologic/Hepatologic Conditions
Systematic review
glomerular nephropathy
epidemiology
business
chronic kidney disease
Kidney disease
Subjects
Details
- ISSN :
- 23272236
- Volume :
- 8
- Database :
- OpenAIRE
- Journal :
- Journal of Health Economics and Outcomes Research
- Accession number :
- edsair.doi.dedup.....2c56f22d34973e9c8f18ecd371838827