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A dynamic reversible phenylboronic acid sensor for real-time determination of protein-carbohydrate interactions on living cancer cells
- Source :
- Chemical communications (Cambridge, England). 58(99)
- Publication Year :
- 2022
-
Abstract
- Real-time detection of glycosylation on label-free cancer cell surfaces is of significance for the diagnosis and treatment of cancer. In this work, we have successfully developed a novel dynamic reversible sensor based on pH-sensitive phenylboronic esters to determine in real-time the binding kinetics of protein-carbohydrate interactions on suspension cancer cell surfaces using a quartz crystal microbalance (QCM) technique.
Details
- ISSN :
- 1364548X
- Volume :
- 58
- Issue :
- 99
- Database :
- OpenAIRE
- Journal :
- Chemical communications (Cambridge, England)
- Accession number :
- edsair.doi.dedup.....2c2ce9dd6baab001f22c0c761cc02dd3