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In patients with advanced ovarian cancer, primary suboptimal surgery has better survival outcome than interval suboptimal surgery
- Source :
- Journal of the Turkish German Gynecological Association, Journal of the Turkish-German Gynecological Association, Vol 20, Iss 1, Pp 31-36 (2019)
- Publication Year :
- 2018
-
Abstract
- Objective: It is known that optimal or complete cytoreduction is the most important factor in patients with advanced ovarian cancer. The aim of this study was to examine the results of patients who did not undergo optimal cytoreduction and to examine subgroup analysis based on neoadjuvant chemotherapy (NAC). Material and Methods: Patients with advanced ovarian cancer and suboptimal surgery were retrospectively reviewed. Results: A total of 99 patients with a median age of 59.0 years (range, 22-87 years) were studied. The median follow-up time was 39±32.7 months, 81 patients (81.8%) died and 18 patients (18.2%) were alive. The five-year survival rate was 27.6%. Of the patients, 37 (37.4%) were underwent surgery after NAC, 62 (62.3%) were primary. More patients with NAC died within 3 years compared with those without NAC (83.9% vs 56.0%) (p=0.015). Patients with NAC had less tumor spread (presence of visible tumor in the upper abdomen during surgery) (29.7% vs 72.6%; p
- Subjects :
- medicine.medical_specialty
Chemotherapy
Proportional hazards model
business.industry
Primary surgery
medicine.medical_treatment
lcsh:R
lcsh:Medicine
Obstetrics and Gynecology
Subgroup analysis
medicine.disease
lcsh:Gynecology and obstetrics
survival
Metastasis
Surgery
Log-rank test
Serous fluid
Medicine
cytoreductive surgery
In patient
business
Survival rate
lcsh:RG1-991
Original Investigation
neoadjuvant chemotherapy
Subjects
Details
- ISSN :
- 13090399
- Volume :
- 20
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Journal of the Turkish German Gynecological Association
- Accession number :
- edsair.doi.dedup.....2b8435c37f4a4b7fe24c5a88e2434b43