Back to Search Start Over

Synthesis and Antiproliferative Activity of [RuCp(PPh3)2(HdmoPTA)](OSO2CF3)2 (HdmoPTA = 3,7-H-3,7-Dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane)

Authors :
Franco Scalambra
Elva Martin-Batista
José M. Padrón
Pablo Lorenzo-Luis
Antonio Romerosa
Zenaida Mendoza
Manuel Serrano-Ruiz
Source :
Inorganic chemistry 55 (2016): 7820–7822. doi:10.1021/acs.inorgchem.6b01207, info:cnr-pdr/source/autori:Mendoza Z.; Lorenzo-Luis P.; Serrano-Ruiz M.; Martin-Batista E.; Padron J.M.; Scalambra F.; Romerosa A./titolo:Synthesis and Antiproliferative Activity of [RuCp(PPh3)2(HdmoPTA)](OSO2CF3)2 (HdmoPTA = 3,7-H-3,7-Dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane)/doi:10.1021%2Facs.inorgchem.6b01207/rivista:Inorganic chemistry/anno:2016/pagina_da:7820/pagina_a:7822/intervallo_pagine:7820–7822/volume:55
Publication Year :
2016

Abstract

The complex [RuCp(PPh3)2(HdmoPTA)](OSO2CF3)2 (2; HdmoPTA = 3,7-H-3,7-dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane) was synthesized and characterized. Its crystal structure was determined by single-crystal X-ray diffraction. The complex showed a more potent antiproliferative activity than cisplatin against a representative panel of human cancer cells.

Details

ISSN :
1520510X
Volume :
55
Issue :
16
Database :
OpenAIRE
Journal :
Inorganic chemistry
Accession number :
edsair.doi.dedup.....2b809c52660cb841b156a7831b40b26e
Full Text :
https://doi.org/10.1021/acs.inorgchem.6b01207