Figure S1-S4 from Host IL11 Signaling Suppresses CD4+ T cell–Mediated Antitumor Responses to Colon Cancer in Mice

Supplementary Figure 1. Gating strategy and representative flow cytometric plots of MC38 tumors from WT and Il11ra-/- hosts. Supplementary Figure 2. IL-11 has no effect on tumor-infiltrating immune cells in MC38 and CT26 tumors from WT and Il11ra-/- hosts. Supplementary Figure 3. IL-11 has no effect on PMA/Iono-induced IFNγ and TNFα production by IL-11RA-deficient CD4+ T cells. Supplementary Figure 4. Single cell profiling of IL11RA and IFNG expression in intra-tumoral CD4+ T cells from colon cancer patients.