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Biogenic Silver Nanoparticles of Clinacanthus nutans as Antioxidant with Antimicrobial and Cytotoxic Effects
- Source :
- Bioinorganic Chemistry and Applications, Vol 2021 (2021)
- Publication Year :
- 2021
- Publisher :
- Hindawi Limited, 2021.
-
Abstract
- Silver nanoparticles (AgNPs) previously synthesised using leaf (AgNP-L) and stem (AgNP-S) extracts of Clinacanthus nutans (C. nutans) were tested to evaluate antimicrobial, antioxidant, and cytotoxicity activities. The AgNPs showed good inhibition against bacteria, but not fungi. The inhibition results showed the highest activity against Staphylococcus aureus (S. aureus) with 11.35 mm (AgNP-L) and 11.52 mm (AgNP-S), while the lowest inhibition was against Escherichia coli (E. coli) with 9.22 mm (AgNP-L) and 9.25 mm (AgNP-S) in the disc diffusion method. The same trend of results was noted in the well diffusion method. The IC50 of AgNP-L and AgNP-S in 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays was 417.05 μg/mL and 434.60 μg/mL, as well as 304.31 μg/mL and 326.83 μg/mL, respectively. Ferric reducing power (FRAP) assay showed that AgNP-L [872.389 μmol/L Fe(II)] and AgNP-S [612.770 μmol/L Fe(II)] exhibited significantly ( p p
- Subjects :
- Antioxidant
Article Subject
DPPH
medicine.medical_treatment
ved/biology.organism_classification_rank.species
02 engineering and technology
Biochemistry
Clinacanthus nutans
Silver nanoparticle
Inorganic Chemistry
HeLa
03 medical and health sciences
chemistry.chemical_compound
medicine
Cytotoxicity
QD146-197
030304 developmental biology
0303 health sciences
ABTS
biology
ved/biology
Organic Chemistry
021001 nanoscience & nanotechnology
biology.organism_classification
Antimicrobial
chemistry
0210 nano-technology
TP248.13-248.65
Biotechnology
Nuclear chemistry
Subjects
Details
- ISSN :
- 1687479X and 15653633
- Volume :
- 2021
- Database :
- OpenAIRE
- Journal :
- Bioinorganic Chemistry and Applications
- Accession number :
- edsair.doi.dedup.....2b3958f35c0a7e70902ce941dae0b9bd