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Granular Cell Tumor Within an Ovarian Mature Cystic Teratoma: Report of a Unique Case and Review of the Literature
- Source :
- International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 36(5)
- Publication Year :
- 2016
-
Abstract
- Granular cell tumors involving the female reproductive tract are rare, with only a small number of cases described. Of the reported cases, none are documented within an ovarian mature cystic teratoma (MCT). This report documents a case of a granular cell tumor, incidentally discovered within an ovarian MCT in a 50-yr-old woman undergoing a supracervical hysterectomy and left salpingo-oophorectomy. Although malignant transformation and other secondary ovarian neoplasms in MCT have been well documented, synchronous nonovarian benign neoplasms are reported much less frequently. The histogenesis of secondary tumors arising in MCT is incompletely understood, and the current case provides additional insight, especially pertaining to schwannian and neuroectodermal tumors arising in this setting. The current case, to the best of our knowledge, represents the first report of a granular cell tumor involving a mature teratoma of any site, with the diagnosis being supported by morphologic and immunohistochemical staining characteristics.
- Subjects :
- 0301 basic medicine
Pathology
medicine.medical_specialty
endocrine system diseases
medicine.medical_treatment
Salpingo-oophorectomy
Histogenesis
Hysterectomy
Pathology and Forensic Medicine
Malignant transformation
Neoplasms, Multiple Primary
03 medical and health sciences
0302 clinical medicine
Supracervical hysterectomy
medicine
Humans
Ovarian Neoplasms
Ovarian mature cystic teratoma
Granular cell tumor
business.industry
Teratoma
Obstetrics and Gynecology
Middle Aged
medicine.disease
030104 developmental biology
Granular Cell Tumor
030220 oncology & carcinogenesis
Immunohistochemistry
Female
business
Subjects
Details
- ISSN :
- 15387151
- Volume :
- 36
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
- Accession number :
- edsair.doi.dedup.....2b1e508fd42f0ab4fd80b66092d885b2