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Dynamics in Endolymphatic Hydrops & Symptoms in Meniere's Disease After Endolymphatic Duct Blockage, Preliminary Results
- Source :
- Frontiers in Neurology, Vol 11 (2021), Frontiers in Neurology
- Publication Year :
- 2021
- Publisher :
- Frontiers Media SA, 2021.
-
Abstract
- Objective: The purpose of the present study was to evaluate the dynamics of endolymphatic hydrops (EH) and symptoms in a group of patients who underwent endolymphatic duct blockage (EDB) for treatment of intractable Meniere's Disease (MD), and to explore a metric for verifying the effectiveness of EDB procedure.Methods: A total of 22 patients with intractable MD patients who underwent EDB participated in the present study. EH was visualized using locally enhanced inner ear magnetic resonance imaging (MRI) prior to and following surgery. The vestibular hydrops ratio (VHR) in the second MRI examination was compared with the pre-surgery recordings.Results: Following EDB, 6 patients exhibited complete or partial reversal of EH, complete control of vertigo spells and reported improvement in hearing; 13 patients showed no changes in EH or hearing, but 5 of these patients exhibited complete control of vertigo attacks, and the other 8 patients exhibited improved control of vertigo attacks. The final 3 patients showed an increase in EH, but symptomatic worsening in 2 patients, and symptomatic improvement in 1 patient. There was a significant difference in the average VHR prior to and following EDB. Postoperative VHR was positively correlated with the frequency of vertigo spells in the latest 6 months of follow-up and improvement of postoperative average hearing threshold.Conclusion: The decreased EH accompanying the reduction in vertigo attacks and hearing preservation may provide a metric for verifying the effectiveness of EDB treatment in patients with MD.
- Subjects :
- endolymphatic duct blockage
lcsh:RC346-429
Endolymphatic duct
Vertigo
otorhinolaryngologic diseases
medicine
Inner ear
Endolymphatic hydrops
lcsh:Neurology. Diseases of the nervous system
Original Research
Vestibular system
Absolute threshold of hearing
treatment
medicine.diagnostic_test
biology
business.industry
Magnetic resonance imaging
dynamics
medicine.disease
biology.organism_classification
Ménière's disease
medicine.anatomical_structure
endolymphatic hydrops
Neurology
Anesthesia
symptoms
Neurology (clinical)
business
Meniere's disease
Subjects
Details
- ISSN :
- 16642295
- Volume :
- 11
- Database :
- OpenAIRE
- Journal :
- Frontiers in Neurology
- Accession number :
- edsair.doi.dedup.....2b008f7c3a7275d975dce2d17ce04d15