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Variable linezolid exposure and response and the role of therapeutic drug monitoring: Case series
- Source :
- Clinical Case Reports, Clinical Case Reports, Vol 8, Iss 7, Pp 1126-1129 (2020)
- Publication Year :
- 2020
- Publisher :
- Wiley, 2020.
-
Abstract
- Two patients with normal renal function, yet each showed unexpected, supra‐ and subtherapeutic linezolid plasma concentrations resulting in toxicity and ineffective therapy, respectively. TDM helps to early identify and correct such excursions.
- Subjects :
- safety
efficacy
lcsh:Medicine
Case Report
thrombocytopenia
Case Reports
linezolid
030204 cardiovascular system & hematology
Pharmacology
03 medical and health sciences
Normal renal function
chemistry.chemical_compound
0302 clinical medicine
Medicine
lcsh:R5-920
medicine.diagnostic_test
business.industry
lcsh:R
General Medicine
monitoring
chemistry
Therapeutic drug monitoring
030220 oncology & carcinogenesis
Toxicity
Linezolid
Plasma concentration
lcsh:Medicine (General)
business
Subjects
Details
- ISSN :
- 20500904
- Volume :
- 8
- Database :
- OpenAIRE
- Journal :
- Clinical Case Reports
- Accession number :
- edsair.doi.dedup.....2af787d550ef7e6526186bf6da89bbb0
- Full Text :
- https://doi.org/10.1002/ccr3.2835