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Corneal Opacity Leading to Multiple Myeloma Diagnosis: A Case Report and Literature Review
- Source :
- The American Journal of Case Reports
- Publication Year :
- 2018
- Publisher :
- International Scientific Information, Inc., 2018.
-
Abstract
- Patient: Female, 54 Final Diagnosis: Multiple myeloma Symptoms: A 9-month history of blurred vision Medication: Systemic chemotherapy with vincristine • cyclophosphamide • dexamethasone Clinical Procedure: Multiple myeloma patient presenting with corneal opacity and blurred vision as chief complaint Specialty: Ophthalmology and Hematology Objective: Rare disease Background: A multiple myeloma patient presenting with corneal opacity and blurred vision as chief complaint is rare. Case Report: A 54-year-old woman with a 9-month history of blurred vision without other systemic symptoms consulted an ophthalmologist. The patient had bilateral diffuse corneal opacity at the corneal epithelium and anterior stroma under slit-lamp examination. Decreased corneal endothelial cells density was found by microscopy. During consultation, the patient was noted to have an anemic face. Laboratory analysis and bone marrow were investigated. Serum protein electrophoresis revealed a raised serum kappa paraprotein band (12.4 g/L). The erythrocyte sedimentation rate (ESR) was accelerated to 49 mm/h (normal
- Subjects :
- medicine.medical_specialty
genetic structures
Biopsy
Bone Marrow Cells
Diagnosis, Differential
03 medical and health sciences
Corneal Opacity
0302 clinical medicine
Blurred vision
Ophthalmology
medicine
Humans
030212 general & internal medicine
Multiple myeloma
Corneal epithelium
medicine.diagnostic_test
business.industry
Endothelium, Corneal
Antibodies, Monoclonal
Articles
General Medicine
Middle Aged
medicine.disease
eye diseases
medicine.anatomical_structure
Erythrocyte sedimentation rate
Serum protein electrophoresis
030221 ophthalmology & optometry
Female
sense organs
Bone marrow
Differential diagnosis
medicine.symptom
Multiple Myeloma
business
Subjects
Details
- ISSN :
- 19415923
- Volume :
- 19
- Database :
- OpenAIRE
- Journal :
- American Journal of Case Reports
- Accession number :
- edsair.doi.dedup.....2aebd2f33386d4c597f1671889d1f17a