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Dynamics of virus shedding and antibody responses in influenza A virus-infected feral swine
- Source :
- Journal of General Virology. 96:2569-2578
- Publication Year :
- 2015
- Publisher :
- Microbiology Society, 2015.
-
Abstract
- Given their free-ranging habits, feral swine could serve as reservoirs or spatially dynamic ‘mixing vessels’ for influenza A virus (IAV). To better understand virus shedding patterns and antibody response dynamics in the context of IAV surveillance amongst feral swine, we used IAV of feral swine origin to perform infection experiments. The virus was highly infectious and transmissible in feral swine, and virus shedding patterns and antibody response dynamics were similar to those in domestic swine. In the virus-inoculated and sentinel groups, virus shedding lasted ≤ 6 and ≤ 9 days, respectively. Antibody titres in inoculated swine peaked at 1 : 840 on day 11 post-inoculation (p.i.), remained there until 21 days p.i. and dropped to
- Subjects :
- Swine Diseases
biology
Swine
Inoculation
Influenza A Virus, H3N2 Subtype
animal diseases
Animals, Wild
Context (language use)
Antibodies, Viral
medicine.disease_cause
Virology
Standard
Virus
Virus Shedding
Nucleoprotein
Serology
Orthomyxoviridae Infections
biology.protein
Influenza A virus
medicine
Animals
Antibody
Viral shedding
Subjects
Details
- ISSN :
- 14652099 and 00221317
- Volume :
- 96
- Database :
- OpenAIRE
- Journal :
- Journal of General Virology
- Accession number :
- edsair.doi.dedup.....2ae746930869779cd6b6f862c881d257