Noncardiac-Related Morbidity, Mobility Limitation, and Outcomes in Older Adults With Heart Failure

Background To examine the individual and combined associations of noncardiac-related conditions and mobility limitation with morbidity and mortality in adults with heart failure (HF). Methods We conducted a retrospective cohort study in a large, diverse group of adults with HF from five U.S. integrated healthcare delivery systems. We characterized patients with respect to the presence of noncardiac conditions ( Results Among 114,553 adults diagnosed with HF (mean age: 73 years old, 46% women), compared with Conclusions There is an additive association of mobility limitation, beyond the burden of noncardiac multimorbidity, on mortality for patients with HF, and especially prominent in younger patients.