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Suppression of synchronous spiking in two interacting populations of excitatory and inhibitory quadratic integrate-and-fire neurons
- Source :
- Physical Review E. 104
- Publication Year :
- 2021
- Publisher :
- American Physical Society (APS), 2021.
-
Abstract
- Collective oscillations and their suppression by external stimulation are analyzed in a large-scale neural network consisting of two interacting populations of excitatory and inhibitory quadratic integrate-and-fire neurons. In the limit of an infinite number of neurons, the microscopic model of this network can be reduced to an exact low-dimensional system of mean-field equations. Bifurcation analysis of these equations reveals three different dynamic modes in a free network: a stable resting state, a stable limit cycle, and bistability with a coexisting resting state and a limit cycle. We show that in the limit cycle mode, high-frequency stimulation of an inhibitory population can stabilize an unstable resting state and effectively suppress collective oscillations. We also show that in the bistable mode, the dynamics of the network can be switched from a stable limit cycle to a stable resting state by applying an inhibitory pulse to the excitatory population. The results obtained from the mean-field equations are confirmed by numerical simulation of the microscopic model.<br />Comment: 11 figures
- Subjects :
- Physics
education.field_of_study
Quantitative Biology::Neurons and Cognition
Bistability
Resting state fMRI
Pulse (signal processing)
Population
FOS: Physical sciences
Nonlinear Sciences - Chaotic Dynamics
Inhibitory postsynaptic potential
Quantitative Biology - Neurons and Cognition
FOS: Biological sciences
Limit cycle
Excitatory postsynaptic potential
Neurons and Cognition (q-bio.NC)
Limit (mathematics)
Chaotic Dynamics (nlin.CD)
education
Biological system
Subjects
Details
- ISSN :
- 24700053 and 24700045
- Volume :
- 104
- Database :
- OpenAIRE
- Journal :
- Physical Review E
- Accession number :
- edsair.doi.dedup.....2ab22fb9043b474ab9e37ab7f016e695