Quantitation and Identification of Thousands of Human Proteoforms below 30 kDa

Authors :: Ryan T. Fellers
Kenneth R. Durbin
Luca Fornelli
Neil L. Kelleher
Masashi Narita
Peter F. Doubleday
Source :: Journal of Proteome Research. 15:976-982
Publication Year :: 2016
Publisher :: American Chemical Society (ACS), 2016.
Abstract: Top-down proteomics is capable of identifying and quantitating unique proteoforms through the analysis of intact proteins. We extended the coverage of the label-free technique, achieving differential analysis of whole proteins