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Iridium oxide (IV) nanoparticle-based lateral flow immunoassay
- Source :
- Recercat. Dipósit de la Recerca de Catalunya, instname, Dipòsit Digital de Documents de la UAB, Universitat Autònoma de Barcelona, Recercat: Dipósit de la Recerca de Catalunya, Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya), Digital.CSIC. Repositorio Institucional del CSIC
- Publication Year :
- 2019
- Publisher :
- Elsevier, 2019.
-
Abstract
- Lateral flow biosensors are paper-based devices that allow the detection of different types of analytes with quickness, robustness and selectivity, without leaving behind paper sensors benefits as low-cost, recyclability and sustainability. Nanomaterials have been widely reported in lateral flow biosensors, offering new sensing strategies based on optical or electrical detection techniques. Looking for other advantageous nanomaterials, we propose for the first time the use of iridium oxide (IV) nanoparticles in lateral flow assays for the detection of human immunoglobulin as a model protein. These nanoparticles can be easily prepared and conjugated with biomarkers. Their dark blue color gives a high contrast against the white background of the strips being in this way excellent labels.<br />We acknowledge support from MINECO (Spain) MAT2017-87202-P and project PCIN-2016-066 (program Euronanomed 2). This work is also funded by the CERCA Programme / Generalitat de Catalunya. ICN2 is supported by the Severo Ochoa program from Spanish MINECO (Grant No. SEV-2017-0706). Daniel Quesada-González and Amadeo Sena-Torralba acknowledge Autonomous University of Barcelona (UAB) for the possibility of performing this work inside the framework of Chemistry and Biotechnology Ph.D. Programmes, respectively.
- Subjects :
- Paper
Analyte
Materials science
Mobile phone sensing
Biomedical Engineering
Biophysics
Nanoparticle
Immunoglobulins
Nanotechnology
02 engineering and technology
Biosensing Techniques
Iridium oxide
Conjugated system
Iridium
01 natural sciences
Paper-based biosensor
Human immunoglobulin
Nanomaterials
Limit of Detection
Lateral flow immunoassay
Electrochemistry
Humans
Reagent Strips
Immunoassay
010401 analytical chemistry
General Medicine
021001 nanoscience & nanotechnology
Iridium oxide nanoparticles
0104 chemical sciences
Nanoparticles
Smartphone
0210 nano-technology
Biosensor
Biotechnology
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Recercat. Dipósit de la Recerca de Catalunya, instname, Dipòsit Digital de Documents de la UAB, Universitat Autònoma de Barcelona, Recercat: Dipósit de la Recerca de Catalunya, Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya), Digital.CSIC. Repositorio Institucional del CSIC
- Accession number :
- edsair.doi.dedup.....2a5d1a760cb2bd06bce033c6296b09a1