Double Face of Statins at the Crossroad of Coronary Atherosclerotic Plaque and Aortic Valve Calcification?

We read with interest the manuscript by Lee et al. [(1)][1], which reports statin use impact on coronary plaque features. Statins increase coronary artery calcification, reducing local inflammation, changing phenotypic plaque composition, and lowering the high-risk plaques, as also observed in