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Activation of cytotoxic lymphocytes in patients with scrub typhus

Authors :
Arjen M. Dondorp
Tom van der Poll
Nicholas J. White
Maaike de Fost
Kriangsak Pimda
Wirongrong Chierakul
Other departments
Amsterdam institute for Infection and Immunity
Infectious diseases
Source :
Scopus-Elsevier, American journal of tropical medicine and hygiene, 72(4), 465-467. American Society of Tropical Medicine and Hygiene
Publication Year :
2016

Abstract

Thai patients with scrub typhus caused by the intracellular pathogen Orientia tsutsugamushi displayed elevated plasma concentrations of granzymes A and B, interferon-gamma (IFN)-gamma-inducible protein 10, and monokine induced by IFN-gamma. These data suggest that activation of cytotoxic lymphocytes is part of the early host response to scrub typhus.

Details

Language :
English
ISSN :
00029637
Database :
OpenAIRE
Journal :
Scopus-Elsevier, American journal of tropical medicine and hygiene, 72(4), 465-467. American Society of Tropical Medicine and Hygiene
Accession number :
edsair.doi.dedup.....2a3816ea1abbc14dd8bcab58e478bab1