The Role of Hypoxia at Primary Dysmenorrhea, Utilizing a Novel Hypoxia Marker—Scube1

Study Objective To determine the SCUBE1 levels in adolescents with primary dysmenorrhea. Design A prospective cross-sectional study. Setting A university hospital outpatient clinic, Rize, Turkey. Participants A total of 40 adolescent girls, 15 on menses and 25 not on menses. Interventions and Main Outcome Measures Demographic features and menstrual history of the participants were assessed and blood samples were obtained for detecting the platelet volume, platelet counts, and SCUBE1 levels of the participants. Results No difference was detected between the 2 groups in mean platelet volume, platelet count, and SCUBE1 levels. Conclusion Future trials are required to investigate the relation between SCUBE1 levels and primary dysmenorrhea.