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Glycemic variability and cardiovascular disease in patients with type 2 diabetes
- Source :
- BMJ Open Diabetes Research & Care, BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)
- Publication Year :
- 2021
- Publisher :
- BMJ Publishing Group, 2021.
-
Abstract
- Glycated hemoglobin is currently the gold standard for assessment of long-term glycemic control and response to medical treatment in patients with diabetes. Glycated hemoglobin, however, does not address fluctuations in blood glucose. Glycemic variability (GV) refers to fluctuations in blood glucose levels. Recent clinical data indicate that GV is associated with increased risk of hypoglycemia, microvascular and macrovascular complications, and mortality in patients with diabetes, independently of glycated hemoglobin level. The use of continuous glucose monitoring devices has markedly improved the assessment of GV in clinical practice and facilitated the assessment of GV as well as hypoglycemia and hyperglycemia events in patients with diabetes. We review current concepts on the definition and assessment of GV and its association with cardiovascular complications in patients with type 2 diabetes.
- Subjects :
- Blood Glucose
medicine.medical_specialty
Cardiovascular and Metabolic Risk
Endocrinology, Diabetes and Metabolism
Type 2 diabetes
Disease
Hypoglycemia
Diseases of the endocrine glands. Clinical endocrinology
chemistry.chemical_compound
diagnostic techniques and procedures
Diabetes mellitus
Internal medicine
Medicine
Humans
In patient
Glycemic
Glycated Hemoglobin
business.industry
Blood Glucose Self-Monitoring
Gold standard
medicine.disease
RC648-665
chemistry
type 2
Diabetes Mellitus, Type 2
Cardiovascular Diseases
diabetes mellitus
cardiovascular system
Glycated hemoglobin
business
Subjects
Details
- Language :
- English
- ISSN :
- 20524897
- Volume :
- 9
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- BMJ Open Diabetes Research & Care
- Accession number :
- edsair.doi.dedup.....2a2bf7b47c3171b886455c4514a04412