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Role of the Endobronchial Landmarks Guiding TBNA and EBUS-TBNA in Lung Cancer Staging
- Source :
- Canadian Respiratory Journal, Vol 2016 (2016), Canadian Respiratory Journal
- Publication Year :
- 2016
- Publisher :
- Hindawi Limited, 2016.
-
Abstract
- Background. Lung cancer is the leading cause of malignancy related mortality in the United States. Accurate staging of NSCLC influences therapeutic decisions. Transbronchial needle aspiration (TBNA) and endobronchial ultrasound-guided TBNA (EBUS-TBNA) has been accepted as a procedure for the diagnosis and staging of lung cancer. The aim of this study is to evaluate the efficacy and adequacy of TBNA and EBUS-TBNA for sampling of mediastinal adenopathy using the Wang’s eleven lymph node map stations. Methods. We retrospectively reviewed 99 consecutive cases diagnosed with malignancy by EBUS-TBNA and a series 74 patients evaluated for mediastinal adenopathy or a pulmonary lesion using conventional transbronchial needle aspiration. The IASLC lymph node map was correlated with Wang’s map. Results. A total of 182 lymph node stations were sampled using EBUS-TBNA. 96 were positive for nodal metastasis. A total of four cases of samples taken from station 2R showed malignant cells. From the 74 cases series using cTBNA 167 nodes were sampled in 222 passes. Lymphoid or malignant tissue was obtained in 67 (91.8%) cases; 55.1% of the nodes were 1 cm or less. Conclusions. The use of the eleven stations described in Wang’s map to guide TBNA of the mediastinal nodes allows sampling of radiologically considered nonpathological nodes. These data suggest that Wang’s map covers the most frequent IASLC nodal stations compromised with metastasis.
- Subjects :
- Pulmonary and Respiratory Medicine
Ebus tbna
medicine.medical_specialty
Lung Neoplasms
Article Subject
Malignancy
Metastasis
Diseases of the respiratory system
03 medical and health sciences
0302 clinical medicine
Humans
Medicine
Sampling (medicine)
Lung cancer
Endoscopic Ultrasound-Guided Fine Needle Aspiration
Lymph node
Neoplasm Staging
Retrospective Studies
RC705-779
business.industry
Retrospective cohort study
medicine.disease
medicine.anatomical_structure
030228 respiratory system
030220 oncology & carcinogenesis
Lymph Nodes
Radiology
Lung cancer staging
business
Research Article
Subjects
Details
- ISSN :
- 19167245 and 11982241
- Volume :
- 2016
- Database :
- OpenAIRE
- Journal :
- Canadian Respiratory Journal
- Accession number :
- edsair.doi.dedup.....2a256b2ff1d75385ad235f108412d6fd