Clinical features of 50 cases of 2019 novel coronavirus in Bandar Abbas, Iran

Background: There is sparse information to describe the clinical features and outcomes of patients infected with coronavirus disease 2019 (COVID-19) Methods: In a single-center retrospective observational study, 50 patients infected with COVID-19 were studied Epidemiological, demographic, clinical, laboratory, radiological, and treatment data were collected and analyzed Outcomes of critically ill patients and noncritically ill patients were compared Results: The mean age of the patients was 48 8 years, with male predominance Dry cough, fever, and dyspnea were the most complaining symptoms on admission Chronic medical illnesses before admission were present in 56% of the patients The most common laboratory abnormalities were lymphopenia, neutrophilia, thrombocytopenia, increased aspartate aminotransferase, high serum creatinine level, elevated lactate dehydrogenase, and increasing ESR and CRP levels Bilateral mixed ground-glass opacity and consolidation were observed in chest CT scan of most patients Some patients required supplemental oxygen and some needed invasive mechanical ventilation Blood oxygen saturation was different between survivors and nonsurvivors 10% of patients died, of whom 60% were men 40% of dead cases had chronic medical illnesses;60% underwent invasive mechanical ventilation Conclusion: Among the patients diagnosed with COVID-19 infection, the frequent clinical presentation was with a wide range of signs and symptoms The laboratory changes suggest that COVID-19 infection may be related to cellular immune deficiency, myocardial, hepatic, and kidney injury Additional research is needed to elucidate COVID-19 pathogenesis © 2021 Iran University of Medical Sciences