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Development and Biological Evaluation of Acyl Protein Thioesterase 1 (APT1) Inhibitors
- Source :
- Angewandte Chemie. 117:5055-5060
- Publication Year :
- 2005
- Publisher :
- Wiley, 2005.
-
Abstract
- Development and biological evaluation of acyl protein thioesterase 1 (APT1) inhibitors are discussed.
- Subjects :
- Time Factors
Peptidomimetic
Drug Evaluation, Preclinical
In Vitro Techniques
PC12 Cells
Catalysis
Structure-Activity Relationship
Structure–activity relationship
Animals
Humans
Enzyme Inhibitors
Biological evaluation
Benzodiazepinones
Molecular Structure
Chemistry
Biological activity
Cell Differentiation
General Chemistry
General Medicine
biological activity
enzyme inhibitors
esterases
peptidomimetics
proteins
Rats
Biochemistry
ras Proteins
Acyl-Protein Thioesterase 1
lipids (amino acids, peptides, and proteins)
Thiolester Hydrolases
Subjects
Details
- ISSN :
- 15213757 and 00448249
- Volume :
- 117
- Database :
- OpenAIRE
- Journal :
- Angewandte Chemie
- Accession number :
- edsair.doi.dedup.....2a08c0bcd2e42ee103045e958920a3fe