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An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment
- Source :
- Jepson, M, Elliott, D, Conefrey, C, Wade, J, Rooshenas, L, Wilson, C, Beard, D J, Blazeby, J M, Birtle, A, Halliday, A, Stein, R, Donovan, J L, Beard, D J, Carr, A, Cook, J A, Cooper, C, Dean, B, Donovan, J L, Gray, A, Gwilym, S, Judge, A, Merritt, N, Moser, J, Rees, J, Rombach, I, Savulescu, J, Tracey, I, Wartolowska, K, Blazeby, J M, Barham, P, Brookes, S T, Crosby, T, Donovan, J L, Falk, S J, Griffin, S M, Hollingworth, W, Hollowood, A D, Krysztopik, R, Lewis, W, Nicklin, J, Streets, C, Strong, S, Titcomb, D, Williams, G, Birtle, A, Bryan, R, Catto, J W, Chester, J, Donovan, J L, French, A, Hall, E, Harris, C, Johnson, M, Jones, R, Keeley, F, Kirkbank, T, Kockelbergh, R, Lewis, R, Newton, M, Powles, T, Waters, R A, Winterbottom, A, Halliday, A, Becquemin, J, Belli, A, Bosiers, M, Cao, P, Davies, C, Donovan, J L, Gray, A, Gough, M, Hayter, E, Leopold, P, Mcdonald, S, Michaels, J, Mihaylova, B, Peto, R, Robertson, S, Rothwell, P M, Scott, R, Thomas, D A, Vermassen, F, Stein, R, Bartlett, J, Cameron, D, Campbell, A, Canney, P, Donovan, J L, Dunn, J, Earl, H, Falzon, M, Francis, A, Hall, P, Harmer, V, Higgins, H, Hiller, L, Hughes-Davies, L, Hulme, C, Macpherson, I R, Makris, A, Marshall, A, McCabe, C, Morgan, A, Pinder, S, Poole, C J, Rea, D W & Stallard, N 2018, ' An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment ', Journal of Clinical Epidemiology . https://doi.org/10.1016/j.jclinepi.2018.02.018, Journal of Clinical Epidemiology, Jepson, M, Elliott, D, Conefrey, C, Wade, J, Rooshenas, L, Wilson, C, Beard, D, Blazeby, J M, Birtle, A, Halliday, A, Stein, R, Donovan, J L, Chemorad Study Group 2018, ' An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment ', Journal of Clinical Epidemiology, vol. 99, pp. 75-83 . https://doi.org/10.1016/j.jclinepi.2018.02.018, Jepson, M, Elliott, D, Conefrey, C, Wade, J, Rooshenas, L, Wilson, C, Beard, D, Blazeby, J M, Birtle, A, Halliday, A, Stein, R, Donovan, J L, Chemorad Study Group 2018, ' An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment ' Journal of Clinical Epidemiology, vol. 99, pp. 75-83 . DOI: 10.1016/j.jclinepi.2018.02.018
- Publication Year :
- 2018
-
Abstract
- Objectives To explore how the concept of randomization is described by clinicians and understood by patients in randomized controlled trials (RCTs) and how it contributes to patient understanding and recruitment. Study Design and Setting Qualitative analysis of 73 audio recordings of recruitment consultations from five, multicenter, UK-based RCTs with identified or anticipated recruitment difficulties. Results One in 10 appointments did not include any mention of randomization. Most included a description of the method or process of allocation. Descriptions often made reference to gambling-related metaphors or similes, or referred to allocation by a computer. Where reference was made to a computer, some patients assumed that they would receive the treatment that was “best for them”. Descriptions of the rationale for randomization were rarely present and often only came about as a consequence of patients questioning the reason for a random allocation. Conclusions The methods and processes of randomization were usually described by recruiters, but often without clarity, which could lead to patient misunderstanding. The rationale for randomization was rarely mentioned. Recruiters should avoid problematic gambling metaphors and illusions of agency in their explanations and instead focus on clearer descriptions of the rationale and method of randomization to ensure patients are better informed about randomization and RCT participation.<br />Highlights • Practices commonly used to describe randomisation in RCT recruitment could confuse patients. • Patients found it difficult to comprehend gambling-related metaphors of randomisation. • Computer-agency descriptions led to patients believing they would receive the best treatment.
- Subjects :
- Randomization
Psychotherapist
Epidemiology
Article
law.invention
03 medical and health sciences
Random Allocation
0302 clinical medicine
Randomized controlled trial
Patient Education as Topic
law
Qualitative research
Agency (sociology)
Journal Article
Humans
030212 general & internal medicine
Decision Making, Computer-Assisted
Randomized Controlled Trials as Topic
Random allocation
Patient Selection
United Kingdom
3. Good health
Comprehension
Patient information
Centre for Surgical Research
030220 oncology & carcinogenesis
Gambling
CLARITY
Randomized controlled trials
Recruitment to RCTs
Metaphor
Observational study
Recruitment
Psychology
Subjects
Details
- Language :
- English
- ISSN :
- 08954356
- Database :
- OpenAIRE
- Journal :
- Jepson, M, Elliott, D, Conefrey, C, Wade, J, Rooshenas, L, Wilson, C, Beard, D J, Blazeby, J M, Birtle, A, Halliday, A, Stein, R, Donovan, J L, Beard, D J, Carr, A, Cook, J A, Cooper, C, Dean, B, Donovan, J L, Gray, A, Gwilym, S, Judge, A, Merritt, N, Moser, J, Rees, J, Rombach, I, Savulescu, J, Tracey, I, Wartolowska, K, Blazeby, J M, Barham, P, Brookes, S T, Crosby, T, Donovan, J L, Falk, S J, Griffin, S M, Hollingworth, W, Hollowood, A D, Krysztopik, R, Lewis, W, Nicklin, J, Streets, C, Strong, S, Titcomb, D, Williams, G, Birtle, A, Bryan, R, Catto, J W, Chester, J, Donovan, J L, French, A, Hall, E, Harris, C, Johnson, M, Jones, R, Keeley, F, Kirkbank, T, Kockelbergh, R, Lewis, R, Newton, M, Powles, T, Waters, R A, Winterbottom, A, Halliday, A, Becquemin, J, Belli, A, Bosiers, M, Cao, P, Davies, C, Donovan, J L, Gray, A, Gough, M, Hayter, E, Leopold, P, Mcdonald, S, Michaels, J, Mihaylova, B, Peto, R, Robertson, S, Rothwell, P M, Scott, R, Thomas, D A, Vermassen, F, Stein, R, Bartlett, J, Cameron, D, Campbell, A, Canney, P, Donovan, J L, Dunn, J, Earl, H, Falzon, M, Francis, A, Hall, P, Harmer, V, Higgins, H, Hiller, L, Hughes-Davies, L, Hulme, C, Macpherson, I R, Makris, A, Marshall, A, McCabe, C, Morgan, A, Pinder, S, Poole, C J, Rea, D W & Stallard, N 2018, ' An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment ', Journal of Clinical Epidemiology . https://doi.org/10.1016/j.jclinepi.2018.02.018, Journal of Clinical Epidemiology, Jepson, M, Elliott, D, Conefrey, C, Wade, J, Rooshenas, L, Wilson, C, Beard, D, Blazeby, J M, Birtle, A, Halliday, A, Stein, R, Donovan, J L, Chemorad Study Group 2018, ' An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment ', Journal of Clinical Epidemiology, vol. 99, pp. 75-83 . https://doi.org/10.1016/j.jclinepi.2018.02.018, Jepson, M, Elliott, D, Conefrey, C, Wade, J, Rooshenas, L, Wilson, C, Beard, D, Blazeby, J M, Birtle, A, Halliday, A, Stein, R, Donovan, J L, Chemorad Study Group 2018, ' An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment ' Journal of Clinical Epidemiology, vol. 99, pp. 75-83 . DOI: 10.1016/j.jclinepi.2018.02.018
- Accession number :
- edsair.doi.dedup.....2949775783d47a2990fa4feffea099b1